Citalopram and Haloperidol: Drug Interaction Guide
Quick answer: This is a major interaction — avoid combining Citalopram and Haloperidol unless specifically directed by your doctor.
How Citalopram interacts with Haloperidol
Both drugs can prolong cardiac repolarization through effects on cardiac potassium channels. Combined use increases the risk of QT prolongation and torsades de pointes.
What you should do
Avoid when possible, especially in patients with cardiac disease, electrolyte disturbance, or other QT-risk factors. If necessary, use ECG and electrolyte monitoring.
Key facts
Severity
Major — avoid combination
Mechanism
Both drugs can prolong cardiac repolarization through effects on cardiac potassium channels. Combined use increases the ...
Action
Avoid when possible, especially in patients with cardiac disease, electrolyte disturbance, or other QT-risk factors. If ...
Frequently asked questions
Can I take Citalopram and Haloperidol together?
No — this combination should generally be avoided. Avoid when possible, especially in patients with cardiac disease, electrolyte disturbance, or other QT-risk factors. If necessary, use ECG and electrolyte monitoring.
What is the severity of this interaction?
The interaction between Citalopram and Haloperidol is classified as Major — avoid combination. Both drugs can prolong cardiac repolarization through effects on cardiac potassium channels. Combined use increases the risk of QT prolongation and torsades de pointes.
What should I do if I'm prescribed both?
Avoid when possible, especially in patients with cardiac disease, electrolyte disturbance, or other QT-risk factors. If necessary, use ECG and electrolyte monitoring. Always consult your prescribing clinician — do not stop or change medications without medical guidance.
Last reviewed: by iMedic Medical Editorial Team. Our editorial process.