Linezolid and Tyramine Rich Foods: Drug Interaction Guide
Quick answer: This is a major interaction — avoid combining Linezolid and Tyramine Rich Foods unless specifically directed by your doctor.
How Linezolid interacts with Tyramine Rich Foods
Linezolid is a reversible non-selective monoamine oxidase inhibitor; concurrent tyramine intake can precipitate a hypertensive crisis through unopposed noradrenaline release.
What you should do
Counsel patients to avoid aged cheeses, cured meats, fermented soy products and tap beer during and for 2 weeks after linezolid therapy.
Key facts
Severity
Major — avoid combination
Mechanism
Linezolid is a reversible non-selective monoamine oxidase inhibitor; concurrent tyramine intake can precipitate a hypert...
Action
Counsel patients to avoid aged cheeses, cured meats, fermented soy products and tap beer during and for 2 weeks after li...
Frequently asked questions
Can I take Linezolid and Tyramine Rich Foods together?
No — this combination should generally be avoided. Counsel patients to avoid aged cheeses, cured meats, fermented soy products and tap beer during and for 2 weeks after linezolid therapy.
What is the severity of this interaction?
The interaction between Linezolid and Tyramine Rich Foods is classified as Major — avoid combination. Linezolid is a reversible non-selective monoamine oxidase inhibitor; concurrent tyramine intake can precipitate a hypertensive crisis through unopposed noradrenaline release.
What should I do if I'm prescribed both?
Counsel patients to avoid aged cheeses, cured meats, fermented soy products and tap beer during and for 2 weeks after linezolid therapy. Always consult your prescribing clinician — do not stop or change medications without medical guidance.
Last reviewed: by iMedic Medical Editorial Team. Our editorial process.