Mao Inhibitor and Tyramine Rich Foods: Drug Interaction Guide

Quick answer: This is a major interaction — avoid combining Mao Inhibitor and Tyramine Rich Foods unless specifically directed by your doctor.

Interaction severity: Major — avoid combination

How Mao Inhibitor interacts with Tyramine Rich Foods

Non-selective MAO inhibitors prevent breakdown of dietary tyramine, causing massive noradrenaline release and hypertensive crisis.

What you should do

Counsel patients to avoid aged cheeses, cured meats, broad beans, and fermented products; provide written dietary guidance during therapy and for two weeks after stopping.

Key facts

Severity

Major — avoid combination

Mechanism

Non-selective MAO inhibitors prevent breakdown of dietary tyramine, causing massive noradrenaline release and hypertensi...

Action

Counsel patients to avoid aged cheeses, cured meats, broad beans, and fermented products; provide written dietary guidan...

Important medical disclaimer: This page provides educational information about drug interactions for general reference. It is not a substitute for professional medical advice, diagnosis, or treatment. Always discuss your specific medications with a qualified healthcare provider before starting, stopping, or changing any treatment. About our editorial team.

Frequently asked questions

Can I take Mao Inhibitor and Tyramine Rich Foods together?

No — this combination should generally be avoided. Counsel patients to avoid aged cheeses, cured meats, broad beans, and fermented products; provide written dietary guidance during therapy and for two weeks after stopping.

What is the severity of this interaction?

The interaction between Mao Inhibitor and Tyramine Rich Foods is classified as Major — avoid combination. Non-selective MAO inhibitors prevent breakdown of dietary tyramine, causing massive noradrenaline release and hypertensive crisis.

What should I do if I'm prescribed both?

Counsel patients to avoid aged cheeses, cured meats, broad beans, and fermented products; provide written dietary guidance during therapy and for two weeks after stopping. Always consult your prescribing clinician — do not stop or change medications without medical guidance.

Last reviewed: by iMedic Medical Editorial Team. Our editorial process.