Sacubitril Valsartan and Sodium Aurothiomalate: Drug Interaction Guide

Quick answer: Sacubitril Valsartan and Sodium Aurothiomalate have a minor interaction — typically manageable with awareness.

Interaction severity: Minor — typically manageable

How Sacubitril Valsartan interacts with Sodium Aurothiomalate

Gold compounds may cause nitritoid reactions, and renin-angiotensin system blockers can increase susceptibility to flushing, hypotension, nausea, and syncope. The mechanism is incompletely defined but is pharmacodynamic.

What you should do

Warn patients about transient flushing or dizziness after gold injections. Monitor blood pressure and symptoms when the combination is used.

Key facts

Severity

Minor — typically manageable

Mechanism

Gold compounds may cause nitritoid reactions, and renin-angiotensin system blockers can increase susceptibility to flush...

Action

Warn patients about transient flushing or dizziness after gold injections. Monitor blood pressure and symptoms when the ...

Important medical disclaimer: This page provides educational information about drug interactions for general reference. It is not a substitute for professional medical advice, diagnosis, or treatment. Always discuss your specific medications with a qualified healthcare provider before starting, stopping, or changing any treatment. About our editorial team.

Frequently asked questions

Can I take Sacubitril Valsartan and Sodium Aurothiomalate together?

Usually yes, with awareness. Warn patients about transient flushing or dizziness after gold injections. Monitor blood pressure and symptoms when the combination is used.

What is the severity of this interaction?

The interaction between Sacubitril Valsartan and Sodium Aurothiomalate is classified as Minor — typically manageable. Gold compounds may cause nitritoid reactions, and renin-angiotensin system blockers can increase susceptibility to flushing, hypotension, nausea, and syncope. The mechanism is incompletely defined but is pharmacodynamic.

What should I do if I'm prescribed both?

Warn patients about transient flushing or dizziness after gold injections. Monitor blood pressure and symptoms when the combination is used. Always consult your prescribing clinician — do not stop or change medications without medical guidance.

Last reviewed: by iMedic Medical Editorial Team. Our editorial process.